Lina Sparrow is an ambitious young lawyer working on a historic class-action suit seeking reparations for the descendants of American slaves. Josephine is a seventeen-year-old house slave who tends to the mistress of a Virginia tobacco farman aspiring artist named Lu Anne Bell.

Alternating between antebellum Virginia and modern-day New York, The House Girl is a searing tale of art, history, love, and secrets that intertwines the stories of two remarkable women.